Search results for " Takotsubo cardiomyopathy"

showing 6 items of 6 documents

Rare cardiomyopathies: Diagnostic features

2013

Cardiomyopathies (CM) are an important and heterogeneous group of diseases affecting the myocardium. They can induce mechanical and/or electrical disorders and are due to a variety of causes, they frequently are genetic. However, since their high number and their clinical complexity, the identification is still a challenge. Echocardiography is a very useful tool in the assessment of CM. In this review we aim to define the typical clinical features and to discuss the main diagnostic tool, above all echocardiography that can help physicians in the correct assessment of CM.

Cardiomyopathy RestrictiveCardiomyopathyRestrictiveReproducibility of ResultsSettore MED/11 - Malattie Dell'Apparato CardiovascolareSensitivity and Specificitycardiomyopahies echocardiographyDiagnosis DifferentialArrhythmogenic Right Ventricular Dysplasia; Cardiomyopathies; Cardiomyopathy Restrictive; Diagnosis Differential; Fabry Disease; Friedreich Ataxia; Humans; Predictive Value of Tests; Reproducibility of Results; Risk Factors; Sensitivity and Specificity; Takotsubo Cardiomyopathy; EchocardiographyFriedreich AtaxiaPredictive Value of TestsRisk FactorsTakotsubo CardiomyopathyEchocardiographyDiagnosisDifferentialFabry DiseaseHumansCardiomyopathiesArrhythmogenic right ventricular dysplasia; Cardiomyopathy restrictive; Fabry diseaseArrhythmogenic Right Ventricular Dysplasia
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G-protein-coupled receptor kinase 5 polymorphism and Takotsubo cardiomyopathy.

2015

BACKGROUND: Takotsubo cardiomyopathy (TTC) is an increasingly reported clinical syndrome that mimics acute myocardial infarction without obstructive coronary artery disease and is characterized by transient systolic dysfunction of the apical and/or mid-segments of the left ventricle. The syndrome mainly occurs in postmenopausal women with high adrenergic state conditions. Nowadays, the pathophysiology of TTC is not yet known and the possibility of a genetic predisposition is controversial. AIMS: The purpose of this study was to assess the genetic susceptibility to TTC through analysis of the L41Q polymorphism of the G-protein-coupled receptor kinase 5 (GRK5). METHODS AND RESULTS: In a cohor…

G-Protein-Coupled Receptor Kinase 5Malemedicine.medical_specialtyCardiomyopathyInfarctionCohort StudiesGene FrequencyG-Protein-Coupled Receptor Kinase 5Takotsubo CardiomyopathyInternal medicineGenotypemedicineGenetic predispositionHumansSettore MED/05 - Patologia ClinicaGenetic Predisposition to Diseasecardiovascular diseasesgenotype G-protein-coupled receptor kinase 5 gene polymorphism Takotsubo cardiomyopathyAgedPolymorphism Geneticbusiness.industryCase-control studyGeneral MedicineMiddle Agedmedicine.diseaseSettore MED/11 - Malattie Dell'Apparato Cardiovascolaremedicine.anatomical_structureVentricleCase-Control StudiesCardiologyFemaleCardiology and Cardiovascular MedicinebusinessCohort study
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Beta-blockers are associated with better long-term survival in patients with Takotsubo syndrome

2022

ObjectiveThe advantage of beta-blockers has been postulated in patients with Takotsubo syndrome (TTS) given the pathophysiological role of catecholamines. We hypothesised that beta-blocker treatment after discharge may improve the long-term clinical outcome in this patient population.MethodsThis was an observational, multicentre study including consecutive patients with TTS diagnosis prospectively enrolled in the Takotsubo Italian Network (TIN) register from January 2007 to December 2018. TTS was diagnosed according to the TIN, Heart Failure Association and InterTAK Diagnostic Criteria. The primary study outcome was the occurrence of all-cause death at the longest available follow-up; secon…

MaleOutcome AssessmentAdrenergic beta-AntagonistsShockCardiogenicHealth CareTinTakotsubo CardiomyopathyHypertensionOutcome Assessment Health CareHumansFemaleCardiomyopathiesCardiology and Cardiovascular MedicineCardiomyopathies; Hypertension; Outcome Assessment Health Care; Adrenergic beta-Antagonists; Aged; Female; Humans; Male; Shock Cardiogenic; Tin; Hypertension; Takotsubo CardiomyopathyAgedHeart
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Risk Stratification Using the CHA(2)DS(2)-VASc Score in Takotsubo Syndrome: Data From the Takotsubo Italian Network

2017

Background The CHA 2 DS 2 ‐VASc score predicts stroke in patients with atrial fibrillation and has been reported to have a prognostic role even in acute coronary syndrome patients. The Takotsubo syndrome is a condition that mimics acute coronary syndrome and may present several complications including stroke. We sought to assess the ability of CHA 2 DS 2 ‐VASc score to predict adverse events in Takotsubo syndrome patients. Methods and Results Overall, 371 Takotsubo syndrome patients were enrolled in a prospective registry. Patients were divided into 3 groups according to the CHA 2 DS 2 ‐VASc score: Group A (≤1), B (2–3), and C (≥4). The median CHA 2 DS 2 ‐VASc score was 3 (interquartile ra…

MalePediatricsArrhythmias030204 cardiovascular system & hematologySeverity of Illness Index0302 clinical medicineRisk FactorsInterquartile rangeOdds RatioCoronary Heart DiseaseProspective StudiesRegistries030212 general & internal medicineMyocardial infarctionDSStrokeTakotsuboOriginal ResearchIncidenceMortality rateanticoagulant cardiovascular events CHA2DS2-VASc score stroke Takotsubo Takotsubo cardiomyopathy. Takotsubo syndromeAtrial fibrillationMiddle AgedPrognosisAnticoagulant; Cardiovascular events; CHA2DS2-VASc score; Stroke; Takotsubo; Takotsubo cardiomyopathy; Takotsubo syndrome; Cardiology and Cardiovascular MedicineStrokeItalyCardiologyFemaleCHA2DS2‐VASc scoreTakotsubo syndromeCardiology and Cardiovascular Medicinemedicine.medical_specialtyAcute coronary syndromeCHA2DS2-VASc scoreCardiomyopathy2Cardiovascular eventRisk Assessment-VASc scorecardiovascular events03 medical and health sciencesInternal medicinemedicineHumansAgedbusiness.industryAnticoagulantAnticoagulantsThrombosisOdds ratiomedicine.diseaseCHA2DS2–VASc scoreCHACerebrovascular Disease/StrokeTakotsubo cardiomyopathybusinessFollow-Up Studies
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Climatic variables in Takotsubo cardiomyopathy: role of temperature

2017

Background Recent studies documented a seasonal (summer) and circadian (morning) temporal distribution of takotsubo cardiomyopathy (TTC). Aim The aim of our study was to investigate whether there is a relationship among season, temperature and the occurrence of TTC. A second aim of our study was the comparison of climatic variables in Takotsubo cardiomyopathy versus acute myocardial infarction (AMI). Methods We enrolled consecutive patients with TTC in three Italian centres and, for comparison consecutive patients with AMI. The frequency of TTC and AMI patients according to month, season and quartiles of temperature (I quartile: 9.8–15-, II quartile: 15–19-, III quartile: 19–25- and IV quar…

Malemedicine.medical_specialtyCardiomyopathyMyocardial Infarction030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineTakotsubo CardiomyopathyInternal medicineMedicineHumanscardiovascular diseases030212 general & internal medicineCircadian rhythmMorningAgedAged 80 and overbusiness.industryIncidenceTemperatureClimatic variablesGeneral MedicineMiddle Agedmedicine.diseaseItalyclimatic variables season Takotsubo cardiomyopathy temperatureCase-Control StudiesCardiologyFemaleSeasonsCardiology and Cardiovascular Medicinebusiness
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Happy heart syndrome. frequency, characteristics, and outcome of takotsubo syndrome triggered by positive life events

2021

Background: The association with a preceding stressor is a characteristic feature of takotsubo syndrome (TTS). Negative emotions before TTS are common and led to the popular term "broken heart syndrome." In contrast, pleasant triggers ("happy heart syndrome") are rare and are scarcely investigated. Objectives: The authors analyzed the frequency, clinical characteristics, and prognostic implications of positive emotional stressors in the multicenter GEIST (GErman-Italian-Spanish Takotsubo) Registry. Methods: Patients enrolled in the registry were categorized according to their stressors. This analysis compared patients with pleasant emotional events with patients with negative emotional even…

malebroken heart syndrome happy heart syndrome outcome takotsubo syndrome (TTS)broken heart syndromeoutcometakotsubo syndrome (TTS)registrieshearttakotsubo cardiomyopathyhumanssyndromebroken heart syndrome; happy heart syndrome; outcome; takotsubo syndrome (TTS); heart; humans; male; registries; syndrome; heart Failure; takotsubo cardiomyopathyhappy heart syndromeheart Failure
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